What is the catalog number for EP-3945?

The catalog number for EP-3945 is T205219.

What sizes are available for EP-3945?

EP-3945 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does EP-3945 come in?

EP-3945 is available in 2 different pack sizes.

EP-3945 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EP-3945?

EP-3945 is manufactured by Molfinity.

What is the estimated delivery time for EP-3945?

Estimated delivery time for EP-3945 is approximately 10 business day(s), depending on your location.

EP-3945

Product Specifications

CAS Number

3057176-00-5

Target

MRGPR

Related Pathways

GPCR/G Protein

Bioactivity

EP-3945 is an agonist of Mas-related G protein-coupled receptors (MRGPR), exhibiting greater potency than the small molecule agonist β-Alanine targeting MRGPRD. MRGPRs play a crucial role in inflammatory itch and pain perception. These receptors interact with Gq (MRGPRX2, MRGPRX4, and MRGPRX1 are coupled with Gq; MRGPRX2 and MRGPRD couple with Gi), with EP-3945 having an EC50 value of 211.6 nM for Gq.