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Antiproliferative agent-66

Product Specifications

Target

Microtubule Associated

Related Pathways

Cytoskeletal Signaling

Bioactivity

Antiproliferative agent-66 (Compound B3) is an antiproliferative compound that induces apoptosis and causes cell cycle arrest. It demonstrates IC50 values ranging from 2.03 to 3.6 μM against SH-SY5Y neuroblastoma, HT-29 colorectal adenocarcinoma, and fibroblasts. Additionally, Antiproliferative agent-66 functions as a microtubule polymerization inhibitor with an IC50 of 0.79 μM.

Smiles

CC1=NC=CN1CC2=CSC(=N2)C3=CC4=CC=CC=C4C=C3

Molecular Formula

C18H15N3S

Molecular Weight

305.397

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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