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VK13

Product Specifications

Target

Cysteine Protease, SARS-CoV

Related Pathways

Proteases/Proteasome, Microbiology/Virology

Bioactivity

VK13 (Compound 6) is a potent inhibitor of human cathepsin L (hCatL) and SARS-CoV-2 3CLpro (3CL-PR), with Ki values of 2.6 nM and 0.55 nM, respectively. It also exhibits activity against CoV-2, with an EC50 value of 1.25 μM.

Smiles

CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=CNC1=O)C=O)NC(=O)C2=CC3=C(N2)C=CC=C3OC

Molecular Formula

C24H28N4O5

Molecular Weight

452.503

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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