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E3 Ligase Ligand-linker Conjugate 170

Product Specifications

CAS Number

2379572-21-9

Target

E3 Ligase Ligand-Linker Conjugate

Related Pathways

PROTAC

Bioactivity

E3 Ligase Ligand-linker Conjugate 170 (Compound I) demonstrates antiproliferative activity in non-Hodgkin's lymphoma SU-DHL-4 cells, with an IC50 of less than 0.2 ?M. This conjugate is composed of an E3 ligase ligand and a linker, making it suitable for use in PROTAC synthesis.

Smiles

O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCC4=CC=C(C=C4F)CN5CC(N6CCOCC6)C5)C3C2=O)CC1

Molecular Formula

C28H30FN5O5

Molecular Weight

535.567

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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