E3 Ligase Ligand-linker Conjugate 170
Product Specifications
CAS Number
2379572-21-9
Target
E3 Ligase Ligand-Linker Conjugate
Related Pathways
PROTAC
Bioactivity
E3 Ligase Ligand-linker Conjugate 170 (Compound I) demonstrates antiproliferative activity in non-Hodgkin's lymphoma SU-DHL-4 cells, with an IC50 of less than 0.2 μM. This conjugate is composed of an E3 ligase ligand and a linker, making it suitable for use in PROTAC synthesis.
Smiles
O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCC4=CC=C(C=C4F)CN5CC(N6CCOCC6)C5)C3C2=O)CC1
Molecular Formula
C28H30FN5O5
Molecular Weight
535.567
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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