Anticancer agent 264
Product Specifications
Target
DNA/RNA Synthesis|||CDK
Related Pathways
Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Bioactivity
Anticanceragent 264 (Compound 5w) is an anticancer compound that exhibits significant antiproliferative activity in tumor cell lines, with an IC50 range of 7.5-33.67 ?M. It notably induces cell cycle arrest at the G2/M phase in MDA-MB-231, MIA PaCa-2, and DU-145 cell lines. This compound reduces key cell cycle proteins CDK1, CDK2, and Cyclin B1 in a dose-dependent manner and has strong binding activity with differentiation inhibitors and DNA-binding proteins. Anticanceragent 264 is useful for research in the cancer disease domain.
Molecular Formula
C23H18ClF5N6O
Molecular Weight
524.87
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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