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AST5902 (trimesylate)

Product Specifications

CAS Number

2929417-90-1

Target

Drug Metabolite, EGFR

Related Pathways

Angiogenesis, Metabolism, JAK/STAT signaling, Tyrosine Kinase/Adaptors

Bioactivity

AST5902 trimesylate is the primary metabolite of Alflutinib (AST2818) both in vivo and in vitro. It exhibits antitumor activity. Alflutinib functions as an EGFR inhibitor.

Smiles

O=C(NC1=CC(NC2=NC(C3=CN(C)C4=C3C=CC=C4)=CC=N2)=C(OCC(F)(F)F)N=C1N(CCNC)C)C=C.O=S(O)(C)=O.O=S(O)(C)=O.O=S(O)(C)=O

Molecular Formula

C30H41F3N8O11S3

Molecular Weight

842.884

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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