TopoII/tubulin-IN-1
Product Specifications
Target
Topoisomerase|||Apoptosis|||Reactive Oxygen Species|||ROS|||Microtubule Associated
Related Pathways
NF-?B|||Metabolism|||DNA Damage/DNA Repair|||Immunology/Inflammation|||Cytoskeletal Signaling|||Apoptosis
Bioactivity
TopoII/tubulin-IN-1 (Compound 1B8) is an inhibitor of TopoII/tubulin. It effectively suppresses the proliferation of tumor cells and reduces ROS levels, while inducing apoptosis and cell cycle arrest, without showing significant cytotoxicity to normal cells. TopoII/tubulin-IN-1 exhibits antitumor activity.
Molecular Formula
C21H18ClN5O3
Molecular Weight
423.85
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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