HNC-1664
Product Specifications
CAS Number
2127358-36-3
Target
Anti-infection, SARS-CoV, DNA/RNA Synthesis, Virus Protease
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Microbiology/Virology
Bioactivity
HNC-1664 is an orally active inhibitor of RNA-dependent RNA polymerase (RdRP) . It exhibits broad-spectrum antiviral activity against coronaviruses, including SARS-CoV-2 wild type and its variants (XBB.1.18, HK.3.1, BF.7.14, BA.1, HCoV-229E, HCoV-OC43), as well as arenaviruses. HNC-1664 also demonstrates anti-infective efficacy in a mouse model infected with the SARS-CoV-2 Delta variant.
Smiles
F[C@@H]1[C@H](N2C=3C(C(I)=C2)=C(C)N=CN3)O[C@H](CO)[C@H]1O
Molecular Formula
C12H13FIN3O3
Molecular Weight
393.153
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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