PBA-1105 TFA
Product Specifications
Target
AUTACs, Autophagy
Related Pathways
PROTAC, Autophagy
Bioactivity
PBA-1105 TFA is an autophagy-targeting chimera (AUTOTAC) that induces p62 self-oligomerization. This compound selectively binds to the exposed hydrophobic regions of misfolded proteins, promoting their degradation through the autophagy (autophagy) pathway. Additionally, PBA-1105 TFA enhances the autophagic flux of Ub-bound aggregates.
Smiles
C1=CC=C(C=C1)CCCC(=O)NCCOCCOCCOCCNCC2=CC(=C(C=C2)OCC3=CC=CC=C3)OCC4=CC=CC=C4.C(=O)(C(F)(F)F)O
Molecular Formula
C41H49F3N2O8
Molecular Weight
754.832
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV809266 1.0 µg DNA
C6orf142 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)
Sign In for Pricing
View Details MBS9921980-01 48 Well
Hamster Beta, Beta-Carotene 9',10'-Oxygenase (BCO2) ELISA Kit
Sign In for Pricing
View Details MBS9921980-02 96 Well
Hamster Beta, Beta-Carotene 9',10'-Oxygenase (BCO2) ELISA Kit
Sign In for Pricing
View Details MBS9921980-03 5x 96 Well
Hamster Beta, Beta-Carotene 9',10'-Oxygenase (BCO2) ELISA Kit
Sign In for Pricing
View Details MBS9921980-04 10x 96 Well
Hamster Beta, Beta-Carotene 9',10'-Oxygenase (BCO2) ELISA Kit
Sign In for Pricing
View Details