CDD-1431
Product Specifications
CAS Number
3034216-31-1
Target
TGF-beta/Smad
Related Pathways
Stem Cells
Bioactivity
CDD-1431 is a highly selective BMPR2 kinase inhibitor with a Kiapp of 20.6 nM. It inhibits BRE reporter gene activity, exhibiting an IC50 of 4.87 μM. BMPs regulate cellular processes across various tissue types such as the kidneys, skeletal muscle, heart, and reproductive organs, and can induce ectopic bone formation.
Smiles
O=C(NCC=1C=CC=C(C1)N2CCN(C3=NC(=NC=C3OC)NC4=CC=CC(=C4)S(=O)(=O)N)CC2)C5=CC=C(C=C5)CCC(=O)NC
Molecular Formula
C33H38N8O5S
Molecular Weight
658.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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