CCR6 antagonist 2
Product Specifications
Target
CCR
Related Pathways
Microbiology/Virology, Immunology/Inflammation, GPCR/G Protein
Bioactivity
CCR6 antagonist2 (Compound 20c) acts as a CCR6 antagonist with a Ki of 1.1 nM. It inhibits CCL20-induced calcium influx with an IC50 of 4.9 nM and suppresses the chemotactic migration of CCR6+ T cells with an IC50 of 190 nM.
Molecular Formula
C19H24N4O4
Molecular Weight
372.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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