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PPARγ modulator-2

Product Specifications

CAS Number

2897652-01-4

Target

PPAR

Related Pathways

DNA Damage/DNA Repair, Metabolism

Bioactivity

PPARγmodulator-2 (Compound (R) -2n) is a reversible modulator of PPARγ, inhibiting the PPARγ ligand-binding domain (LBD) with an IC50 of 41 nM. It helps lower blood glucose levels, improves glucose tolerance and insulin sensitivity, and demonstrates antidiabetic activity in db/db mouse models.

Smiles

O=S(=O)(OC=1C=CC(=CC1)S2(=O)=N[Se]C=3C=C(OS(=O)(=O)C4=CC=C(C=C4)C)C=CC32)C5=CC=C(C=C5)C

Molecular Formula

C26H21NO7S3Se

Molecular Weight

634.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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