PPAR? modulator-2
Product Specifications
CAS Number
2897652-01-4
Target
PPAR
Related Pathways
DNA Damage/DNA Repair|||Metabolism
Bioactivity
PPAR?modulator-2 (Compound (R) -2n) is a reversible modulator of PPAR?, inhibiting the PPAR? ligand-binding domain (LBD) with an IC50 of 41 nM. It helps lower blood glucose levels, improves glucose tolerance and insulin sensitivity, and demonstrates antidiabetic activity in db/db mouse models.
Smiles
O=S(=O)(OC=1C=CC(=CC1)S2(=O)=N[Se]C=3C=C(OS(=O)(=O)C4=CC=C(C=C4)C)C=CC32)C5=CC=C(C=C5)C
Molecular Formula
C26H21NO7S3Se
Molecular Weight
634.6
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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