Antitumor agent-196

Product Specifications

CAS Number

2705841-17-2

Target

Caspase|||Apoptosis|||Ferroptosis

Related Pathways

Proteases/Proteasome|||Apoptosis

Bioactivity

Antitumor agent-196 (Compound 6a (?, ?, ?) ) is an artemisinin-based oligomer with anticancer properties, exhibiting an IC50 of 90 nM against MCF-7 breast cancer cells. This compound induces apoptosis by modulating the Bax-caspase 3 signaling pathway and triggers ferroptosis by regulating key signaling molecules (including GPX4) . Antitumor agent-196 shows potential for cancer research applications.

Smiles

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