What is the catalog number for Pyrimidinone 8?

The catalog number for Pyrimidinone 8 is T205042.

What sizes are available for Pyrimidinone 8?

Pyrimidinone 8 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does Pyrimidinone 8 come in?

Pyrimidinone 8 is available in 2 different pack sizes.

Is Pyrimidinone 8 in stock?

Pyrimidinone 8 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Pyrimidinone 8?

Pyrimidinone 8 is manufactured by Molfinity.

What is the estimated delivery time for Pyrimidinone 8?

Estimated delivery time for Pyrimidinone 8 is approximately 10 business day(s), depending on your location.

Pyrimidinone 8

Product Specifications

CAS Number

65004-42-4

Target

Ferroportin

Related Pathways

Membrane transporter/Ion channel

Bioactivity

Pyrimidinone 8 is a reversible, linear non-competitive inhibitor of divalent metal transporter 1 (DMT1) with a Ki of 20 μM (hDMT1) . It does not affect the surface expression of hDMT1 and is not influenced by extracellular pH. Pyrimidinone 8 inhibits hDMT1-mediated iron uptake, with an IC50 of 13.8 μM.