W23-1006
Product Specifications
CAS Number
3035498-92-8
Target
Apoptosis, ALK
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Apoptosis
Bioactivity
W23-1006 is a selective covalent ALKBH5 inhibitor. It binds to the ALKBH5 C200 residue with an IC50 value of 3.848 μM. The inhibitory activity of W23-1006 is approximately 30 times stronger than that of FTO and 8 times greater than that of ALKBH3. W23-1006 is applicable for research in triple-negative breast cancer (TNBC) .
Smiles
O=C1NN(C(=O)C1=CC2=CC(Br)=CC(=C2)N(=O)=O)C3=CC=C(OC)C=C3
Molecular Formula
C17H12BrN3O5
Molecular Weight
418.198
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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