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UniPR500

Product Specifications

CAS Number

2085767-98-0

Target

Ephrin Receptor

Related Pathways

Tyrosine Kinase/Adaptors

Bioactivity

UniPR500, a derivative of UniPR129, is a competitive antagonist for the EphA2 receptor, with a Ki of 0.78 μM. It reduces the binding of biotinylated Ephrin-A1 to EphA2 in a dose-dependent manner, exhibiting an IC50 value of 1.1 μM.

Smiles

C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(CC(=NO)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(N[C@@H](CC=5C=6C(NC5)=CC=CC6)CC(O)=O)=O)C)[H])[H]

Molecular Formula

C36H51N3O4

Molecular Weight

589.808

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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