UniPR500
Product Specifications
CAS Number
2085767-98-0
Target
Ephrin Receptor
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
UniPR500, a derivative of UniPR129, is a competitive antagonist for the EphA2 receptor, with a Ki of 0.78 ?M. It reduces the binding of biotinylated Ephrin-A1 to EphA2 in a dose-dependent manner, exhibiting an IC50 value of 1.1 ?M.
Smiles
C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(CC(=NO)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(N[C@@H](CC=5C=6C(NC5)=CC=CC6)CC(O)=O)=O)C)[H])[H]
Molecular Formula
C36H51N3O4
Molecular Weight
589.808
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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