TrxR1-IN-2
Product Specifications
Target
Apoptosis, Ferroptosis
Related Pathways
Apoptosis
Bioactivity
TrxR1-IN-2 (Compound 6a) acts as a TrxR1 inhibitor that covalently bonds with the Cys475 and Sec498 sites of TrxR1. This interaction hampers TrxR1 activity, resulting in a redox homeostasis disruption and inducing apoptosis and ferroptosis.
Smiles
CCCNC(=O)O[C@@H]1/C=C(/C[C@H]2C=C(C[C@H]3[C@H]1C(=C)C(=O)O3)C(=O)O2)\C
Molecular Formula
C19H23NO6
Molecular Weight
361.389
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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