2DII

MTOR

PI3K/Akt/mTOR signaling

2DII is a potent and selective mTORC2 inhibitor. It specifically binds to the mSin1 PH domain, resulting in a decreased phosphorylation of AKT1.

CCCCCC/C=C\CCCCCCCC(=O)NC[C@@H](C(=O)N)NC(=O)COCCOCCNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@@H]2CCCN2C(=O)C3=CC(=C(C=C3)OC)S(=O)(=O)NCC4=CC=C(C=C4)Cl

C54H76ClN7O11S

1066.74

Ice Packs

-20°C