V-161
Product Specifications
CAS Number
69570-95-2
Target
ATPase, Antibacterial
Related Pathways
Membrane transporter/Ion channel, Microbiology/Virology
Bioactivity
V-161 is an orally active Na+-V-ATPase inhibitor with an IC50 of 144 nM. Under alkaline conditions, V-161 inhibits Enterococcus hirae and vancomycin-resistant Enterococcus faecium (VRE), with MIC values of 4 μg/mL for both. Additionally, V-161 can inhibit the colonization of VRE in the mouse small intestine.
Smiles
N=1C2=CC(=CC=C2NC1C=3C=CC(=CC3)N(C)C)C
Molecular Formula
C16H17N3
Molecular Weight
251.326
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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