What is the catalog number for EGFR-IN-141?

The catalog number for EGFR-IN-141 is T204963.

What sizes are available for EGFR-IN-141?

EGFR-IN-141 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does EGFR-IN-141 come in?

EGFR-IN-141 is available in 2 different pack sizes.

Is EGFR-IN-141 in stock?

EGFR-IN-141 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFR-IN-141?

EGFR-IN-141 is manufactured by Molfinity.

What is the estimated delivery time for EGFR-IN-141?

Estimated delivery time for EGFR-IN-141 is approximately 10 business day(s), depending on your location.

EGFR-IN-141

Product Specifications

CAS Number

3054263-27-0

Target

Apoptosis, EGFR

Related Pathways

JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis

Bioactivity

EGFR-IN-141 (Compound 8I) functions as an EGFR inhibitor with an IC50 of 2.67 nM. It exhibits cytotoxicity in A549 cancer cells with an IC50 of 13.75 μM. EGFR-IN-141 induces apoptosis and mitochondrial membrane depolarization and shows potential antitumor activity.