BC13

Product Specifications

Target

Reactive Oxygen Species, Epigenetic Reader Domain, Apoptosis, DNA/RNA Synthesis, CDK

Related Pathways

Apoptosis, Immunology/Inflammation, Metabolism, NF-κB, Chromatin/Epigenetic, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

Bioactivity

BC13 is a CDK6/BRD4 inhibitor with IC50 values of 234 nM for CDK6 and 36 nM for BRD4. It exhibits antiproliferative properties, induces apoptosis (cell death) and DNA damage, and elevates ROS levels.

Smiles

CC1=CC(=O)N(C2=NC(=NC=C12)N3CCC4(CC3)CN(C4)C(=O)C5=CC=C(C=C5)C6=NC7=C(C(=CC(=C7)OC)OC)C(=O)N6)C8CCCC8

Molecular Formula

C37H39N7O5

Molecular Weight

661.75

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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