BC13
Product Specifications
Target
Reactive Oxygen Species|||Epigenetic Reader Domain|||Apoptosis|||DNA/RNA Synthesis|||CDK
Related Pathways
Apoptosis|||Immunology/Inflammation|||Metabolism|||NF-?B|||Chromatin/Epigenetic|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Bioactivity
BC13 is a CDK6/BRD4 inhibitor with IC50 values of 234 nM for CDK6 and 36 nM for BRD4. It exhibits antiproliferative properties, induces apoptosis (cell death) and DNA damage, and elevates ROS levels.
Smiles
CC1=CC(=O)N(C2=NC(=NC=C12)N3CCC4(CC3)CN(C4)C(=O)C5=CC=C(C=C5)C6=NC7=C(C(=CC(=C7)OC)OC)C(=O)N6)C8CCCC8
Molecular Formula
C37H39N7O5
Molecular Weight
661.75
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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