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Aromatase-IN-4

Product Specifications

CAS Number

3060588-16-8

Target

Cytochromes P450

Related Pathways

Metabolism

Bioactivity

Aromatase-IN-4 (Compound 6a) is an inhibitor of the enzyme aromatase. It displays anticancer properties, with GI50 values for different cell lines as follows: 2.95 μM for MDAMB-231, 3.35 μM for MCF-7, 2.27 μM for A-549, 8.46 nM for NCI-H23, and 1.56 μM for A-498. Aromatase-IN-4 effectively blocks the estrogen production that depends on aromatase.

Smiles

N=1C=CC=C(C1)NC2=NC=C(C=C2)NC=3C=CC(=CC3)C4=NC=5C=CC=CC5N4

Molecular Formula

C23H18N6

Molecular Weight

378.429

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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