Aromatase-IN-4
Product Specifications
CAS Number
3060588-16-8
Target
Cytochromes P450
Related Pathways
Metabolism
Bioactivity
Aromatase-IN-4 (Compound 6a) is an inhibitor of the enzyme aromatase. It displays anticancer properties, with GI50 values for different cell lines as follows: 2.95 μM for MDAMB-231, 3.35 μM for MCF-7, 2.27 μM for A-549, 8.46 nM for NCI-H23, and 1.56 μM for A-498. Aromatase-IN-4 effectively blocks the estrogen production that depends on aromatase.
Smiles
N=1C=CC=C(C1)NC2=NC=C(C=C2)NC=3C=CC(=CC3)C4=NC=5C=CC=CC5N4
Molecular Formula
C23H18N6
Molecular Weight
378.429
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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