VEGFR-2-IN-61
Product Specifications
Target
Apoptosis, VEGFR, Reactive Oxygen Species, ROS
Related Pathways
Apoptosis, Metabolism, Angiogenesis, Immunology/Inflammation, Tyrosine Kinase/Adaptors, NF-κB
Bioactivity
VEGFR-2-IN-61 (Compound 7b) is an inhibitor of VEGFR-2 with an IC50 of 2.83 μM. It effectively inhibits the proliferation of various cancer cells, including MCF-7 cells, with an IC50 of 2.12 μM. Additionally, VEGFR-2-IN-61 suppresses cell migration and induces oxidative stress and apoptosis in MCF-7 cells.
Smiles
CC(C)C1=CC=C(C=C1)NC(=O)C2=C(N(N=C2C3=CNC4=CC=CC=C43)C5=CC=CC=C5)N
Molecular Formula
C27H25N5O
Molecular Weight
435.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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