PROTAC XPO1 degrader-1
Product Specifications
Target
NF-?B|||CRM1|||PROTACs|||Apoptosis
Related Pathways
Apoptosis|||PROTAC|||NF-?B|||Membrane transporter/Ion channel
Bioactivity
PROTAC XPO1 degrader-1 (Compound 2c) is an XPO1 degrader. It exhibits anti-proliferative effects, induces apoptosis, inhibits NF-?B activity, and causes cell cycle arrest at the G1 phase. PROTAC XPO1 degrader-1 is applicable to research on hematological malignancies.
Smiles
CC1=C(C(=O)N(C1=O)NC2=NC(=C(C=C2)C(F)(F)F)Cl)CCC(=O)NCC3CCN(CC3)C4=CC=CC(=C4OC)C(=O)NC5CCC(=O)NC5=O
Molecular Formula
C33H35ClF3N7O7
Molecular Weight
734.122
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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