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BIHC

Product Specifications

CAS Number

1642826-40-1

Target

EGFR, Integrin

Related Pathways

JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling

Bioactivity

BIHC is a Her2-CD3 bispecific antibody, constructed from an anti-Her2 single-domain antibody and an anti-CD3 single-chain variable fragment (Fv) in an IgG-like format. BIHC demonstrates effective in vivo antitumor activity, specifically binding to Her2-expressing tumor cells and efficiently killing Her2-positive cancer cells by recruiting T cells, thus serving as a research tool for Her2-positive cancers.

Smiles

O=C1OC=2C=CC=CC2C(O)=C1C(C=3NC(=NC3Cl)CCCC)C=4C(=O)OC=5C=CC=CC5C4O

Molecular Formula

C26H21ClN2O6

Molecular Weight

492.908

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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