BRD4 Inhibitor-38
Product Specifications
Target
Interleukin|||Epigenetic Reader Domain|||TNF
Related Pathways
Apoptosis|||Chromatin/Epigenetic|||Immunology/Inflammation
Bioactivity
BRD4 Inhibitor-38 (Compound 25) is an orally active BRD4 inhibitor, exhibiting IC50 values of 3.64 ?M for BRD4 BD1 and 0.12 ?M for BRD4 BD2. It also demonstrates anti-inflammatory properties, with an IC50 value of 1.98 ?M for nitric oxide (NO) production.
Smiles
COC1=CC=C(C=C1)/C=C/C2=NC3=C(C(=CC(=C3)OC)OC)C(=O)N2
Molecular Formula
C19H18N2O4
Molecular Weight
338.357
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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