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PARP1-IN-35

Product Specifications

Target

PARP

Related Pathways

Chromatin/Epigenetic, DNA Damage/DNA Repair

Bioactivity

PARP1-IN-35 (compound T26) is a selective, orally active PARP1 inhibitor that can cross the blood-brain barrier, with IC50 values of 0.2 nM for PARP1 and 122 nM for PARP2. It exhibits antiproliferative and anticancer activities and holds potential for breast cancer research.

Smiles

CCC1=CC2=C(C=C(C=N2)CN3CCC(=CC3)C4=NC=C(C=C4)C#N)NC1=O

Molecular Formula

C22H21N5O

Molecular Weight

371.435

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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