PARP1-IN-35
Product Specifications
Target
PARP
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
PARP1-IN-35 (compound T26) is a selective, orally active PARP1 inhibitor that can cross the blood-brain barrier, with IC50 values of 0.2 nM for PARP1 and 122 nM for PARP2. It exhibits antiproliferative and anticancer activities and holds potential for breast cancer research.
Smiles
CCC1=CC2=C(C=C(C=N2)CN3CCC(=CC3)C4=NC=C(C=C4)C#N)NC1=O
Molecular Formula
C22H21N5O
Molecular Weight
371.435
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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