Tubulin inhibitor 49
Product Specifications
CAS Number
1023875-75-3
Target
Microtubule Associated|||Cell Cycle Arrest
Related Pathways
Cytoskeletal Signaling|||Cell Cycle/Checkpoint
Purity
0.9915
Bioactivity
Tubulin inhibitor 49 (Compound 18) is a tubulin polymerization inhibitor (IC50 = 48 ?M) that disrupts the cellular microtubule network, arresting the cell cycle at G2 phase. It exhibits toxicity toward HeLa cells (IC50 = 8.8 ?M) .
Smiles
O=C(NC=1C=CC(=CC1)C=2N=C(SC2)NC3=CC=CC(=C3)C(F)(F)F)C
Molecular Formula
C18H14F3N3OS
Molecular Weight
377.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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