L-657926
Product Specifications
CAS Number
113243-00-8
Target
Prostaglandin Receptor
Related Pathways
Immunology/Inflammation, GPCR/G Protein
Bioactivity
L-657926 is a stereoselective antagonist of the thromboxane A2 (TxA2) receptor, composed of (-) -9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid and (+) -9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid. The IC50 values for the (-) and (+) configurations against TxA2 are 0.27 nM and 124 nM, respectively.
Smiles
C(N1C2=C(C=3C1=CC=C(F)C3)CCC[C@H]2CC(O)=O)C4=CC=C(Cl)C=C4
Molecular Formula
C21H19ClFNO2
Molecular Weight
371.832
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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