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HDAC-IN-84

Product Specifications

Target

Apoptosis|||HDAC

Related Pathways

DNA Damage/DNA Repair|||Apoptosis|||Chromatin/Epigenetic

Bioactivity

HDAC-IN-84 (compound 4a) is a potent HDAC inhibitor with IC50 values of 0.0045, 0.015, 0.013, 0.038, 5.8, and 26 ?M for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC11, respectively. It effectively inhibits the proliferation of leukemia cells without causing toxicity.

Smiles

COC1=CC=C(C=C1)C2=CSC(=N2)C(=O)NOCCCCCC(=O)NO

Molecular Formula

C17H21N3O5S

Molecular Weight

379.431

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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