HDAC-IN-84
Product Specifications
Target
Apoptosis|||HDAC
Related Pathways
DNA Damage/DNA Repair|||Apoptosis|||Chromatin/Epigenetic
Bioactivity
HDAC-IN-84 (compound 4a) is a potent HDAC inhibitor with IC50 values of 0.0045, 0.015, 0.013, 0.038, 5.8, and 26 ?M for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC11, respectively. It effectively inhibits the proliferation of leukemia cells without causing toxicity.
Smiles
COC1=CC=C(C=C1)C2=CSC(=N2)C(=O)NOCCCCCC(=O)NO
Molecular Formula
C17H21N3O5S
Molecular Weight
379.431
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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