TS-IN-5
Product Specifications
Target
DNA/RNA Synthesis|||Bcl-2 Family|||Apoptosis|||PI3K|||STAT
Related Pathways
Cell Cycle/Checkpoint|||PI3K/Akt/mTOR signaling|||Stem Cells|||JAK/STAT signaling|||Apoptosis|||DNA Damage/DNA Repair
Bioactivity
TS-IN-5 (Compound 15) is an inhibitor of thymidylate synthase (TS) . It induces apoptosis by modulating the proteins Bax, BCL-2, PI3K, and STAT1. TS-IN-5 exhibits antitumor activity against liver cancer, breast cancer, and colon cancer.
Smiles
CN1CCN(CC1)C2=NC=C(C(=O)N2)C3=NC4=CC=CC=C4S3
Molecular Formula
C16H17N5OS
Molecular Weight
327.404
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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