EGFR-IN-143
Product Specifications
Target
EGFR, Apoptosis
Related Pathways
Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Apoptosis
Bioactivity
EGFR-IN-143 (Compound 5f) is a potent EGFR inhibitor with an IC50 value of 0.15 μM. It induces apoptosis by arresting the cell cycle at the G2/M phase and exhibits antitumor activity.
Smiles
CCCN1N=C(C(=N1)NC2=CC=C(C=C2)Cl)C(=O)N/N=C\C3=CC(=C(C=C3)O)OC
Molecular Formula
C20H21ClN6O3
Molecular Weight
428.872
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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