WIZ degrader 8
Product Specifications
CAS Number
2879251-26-8
Target
Histone Acetyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
WIZ degrader 8 (compound 10) is a potent and selective molecular glue degrader of the transcription factor WIZ, effectively inducing HbF expression. It promotes WIZ degradation and HbF induction, suggesting its potential use as an inhibitor for sickle cell disease.
Smiles
O=C1N(CC=2C1=CC=C(O[C@H]3CN(CC)C[C@H](C)C3)C2)C4C(=O)NC(=O)CC4
Molecular Formula
C21H27N3O4
Molecular Weight
385.457
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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