What is the catalog number for EGFR-IN-139?

The catalog number for EGFR-IN-139 is T204772.

What sizes are available for EGFR-IN-139?

EGFR-IN-139 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does EGFR-IN-139 come in?

EGFR-IN-139 is available in 2 different pack sizes.

Is EGFR-IN-139 in stock?

EGFR-IN-139 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFR-IN-139?

EGFR-IN-139 is manufactured by Molfinity.

What is the estimated delivery time for EGFR-IN-139?

Estimated delivery time for EGFR-IN-139 is approximately 10 business day(s), depending on your location.

EGFR-IN-139

Product Specifications

CAS Number

1574321-31-5

Target

EGFR

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

Bioactivity

EGFR-IN-139 (compound PD 18) is an EGFR inhibitor with IC50 values of 12.88 nM (wild type), 10.84 nM (L858R/T790M), and 42.68 nM (L858R/T790M/C797S) . It demonstrates significant anticancer activity against the A549 and H1975 cancer cell lines, which express high levels of EGFR. EGFR-IN-139 exhibits strong selectivity for cancer cells and can be utilized in research on non-small cell lung cancer (NSCLC) .