TMPRSS6-IN-1 TFA
Product Specifications
Target
Serine Protease
Related Pathways
Proteases/Proteasome
Bioactivity
TMPRSS6-IN-1 (TFA) is a potent inhibitor of TMPRSS6 (Matriptase-2), a member of the TTSP family (a type of transmembrane serine protease) . TMPRSS6 is a type II TTSP, and genetically reduced levels of TMPRSS6 have been shown to improve symptoms of hemochromatosis and ?-thalassemia in mice.
Smiles
CC(C)[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)C1=NC2=CC=CC=C2S1)NC(=O)[C@H](CC3=CSC=N3)NC(=O)CCC4=CC=CC=C4.C(=O)(C(F)(F)F)O
Molecular Formula
C35H41F3N8O6S2
Molecular Weight
790.875
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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PSME2 (Proteasome Activator Complex Subunit 2, Proteasome Activator 28 Subunit beta, PA28beta, PA28b, Activator Of Multicatalytic Protease Subunit 2, 11S Regulator Complex Subunit beta, REG-beta) (PE)
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