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TMPRSS6-IN-1 TFA

Product Specifications

Target

Serine Protease

Related Pathways

Proteases/Proteasome

Bioactivity

TMPRSS6-IN-1 (TFA) is a potent inhibitor of TMPRSS6 (Matriptase-2), a member of the TTSP family (a type of transmembrane serine protease) . TMPRSS6 is a type II TTSP, and genetically reduced levels of TMPRSS6 have been shown to improve symptoms of hemochromatosis and ?-thalassemia in mice.

Smiles

CC(C)[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)C1=NC2=CC=CC=C2S1)NC(=O)[C@H](CC3=CSC=N3)NC(=O)CCC4=CC=CC=C4.C(=O)(C(F)(F)F)O

Molecular Formula

C35H41F3N8O6S2

Molecular Weight

790.875

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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