PDE5-IN-13
Product Specifications
Target
PDE
Related Pathways
Metabolism
Bioactivity
PDE5-IN-13 (Compound 14b) inhibits phosphodiesterase 5 (PDE5A) with an IC50 of 3 nM and is applicable in pulmonary arterial hypertension research. It demonstrates high selectivity for its target compared to PDE1, PDE2, PDE3, PDE4, PDE7, PDE8, PDE9, PDE10, and PDE11, and it possesses oral bioavailability.
Smiles
C[C@H](C1=CC=CC=N1)NC2=CC=CC3=C2N(C(=O)C(=C3C4=CC=C(C=C4)OC)C#N)CC5=CC=CC=C5
Molecular Formula
C31H26N4O2
Molecular Weight
486.564
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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