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BPD

Product Specifications

CAS Number

213481-12-0

Target

COX, NF-κB

Related Pathways

Neuroscience, Immunology/Inflammation, NF-κB

Bioactivity

BPD is a COX-2 and TAK1-NF-κB inhibitor with an IC50 of 18.5 μM for COX-2. It suppresses the expression of iNOS, TNF-α, IL-6, and IL-1β at the transcriptional level. BPD possesses anti-inflammatory properties and can inhibit carrageenan-induced paw edema as well as LPS-induced septic death.

Smiles

O=C1OC(=O)C(C=2C=CC=3OCOC3C2)=C1C=4C=CC=CC4

Molecular Formula

C17H10O5

Molecular Weight

294.258

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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