BPD
Product Specifications
CAS Number
213481-12-0
Target
COX|||NF-?B
Related Pathways
Neuroscience|||Immunology/Inflammation|||NF-?B
Bioactivity
BPD is a COX-2 and TAK1-NF-?B inhibitor with an IC50 of 18.5 ?M for COX-2. It suppresses the expression of iNOS, TNF-?, IL-6, and IL-1? at the transcriptional level. BPD possesses anti-inflammatory properties and can inhibit carrageenan-induced paw edema as well as LPS-induced septic death.
Smiles
O=C1OC(=O)C(C=2C=CC=3OCOC3C2)=C1C=4C=CC=CC4
Molecular Formula
C17H10O5
Molecular Weight
294.258
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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