NOX4-IN-1
Product Specifications
Target
NADPH, Reactive Oxygen Species, ROS, TGF-beta/Smad
Related Pathways
NF-κB, Immunology/Inflammation, Stem Cells, Metabolism
Bioactivity
NOX4-IN-1 (Compound 14m) is an inhibitor of NADPH oxidase 4 (NOX4) that reduces the production of reactive oxygen species (ROS) . It also inhibits the TGF-β1/Smad signaling pathway, leading to decreased expression of fibrosis-related proteins. Additionally, NOX4-IN-1 impedes the migration of NRK-49F cells.
Smiles
CN1C=CC2=C1C=CC(=C2)C3=C(C=C4C(=C3)C(=O)C=C(O4)NC(=O)C5=CC=CC(=C5)C#N)Cl
Molecular Formula
C26H16ClN3O3
Molecular Weight
453.877
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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