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WNT7A-IN-1

Product Specifications

CAS Number

29133-39-9

Target

Wnt/beta-catenin

Related Pathways

Stem Cells, Cytoskeletal Signaling

Bioactivity

WNT7A-IN-1 (1365-0109) is an inhibitor of WNT7A that disrupts the protein-protein interaction between WNT7A and its receptor FZD5, resulting in the upregulation of MHC-I expression. It significantly increases the expression of MHC-I and p-p65 while reducing the expression of active β-catenin.

Smiles

O=S(=O)([O-])CCC[N+]1=C(OC2=CC=C(C=C21)C=3C=CC=CC3)C=C(C=C4OC=5C=CC(=CC5N4CCCS(=O)(=O)O)C=6C=CC=CC6)CC

Molecular Formula

C37H36N2O8S2

Molecular Weight

700.82

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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