WNT7A-IN-1
Product Specifications
CAS Number
29133-39-9
Target
Wnt/beta-catenin
Related Pathways
Stem Cells, Cytoskeletal Signaling
Bioactivity
WNT7A-IN-1 (1365-0109) is an inhibitor of WNT7A that disrupts the protein-protein interaction between WNT7A and its receptor FZD5, resulting in the upregulation of MHC-I expression. It significantly increases the expression of MHC-I and p-p65 while reducing the expression of active β-catenin.
Smiles
O=S(=O)([O-])CCC[N+]1=C(OC2=CC=C(C=C21)C=3C=CC=CC3)C=C(C=C4OC=5C=CC(=CC5N4CCCS(=O)(=O)O)C=6C=CC=CC6)CC
Molecular Formula
C37H36N2O8S2
Molecular Weight
700.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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