SCH-23390
Product Specifications
CAS Number
87075-17-0
Target
Dopamine Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
SCH-23390 is a dopamine D1-like receptor antagonist (with Ki values of 0.2 nM for the D1 receptor subtype and 0.3 nM for the D5 receptor subtype) . It reduces the latency of lever pressing behavior induced by cocaine in rats. Additionally, SCH-23390 can eliminate generalized seizures triggered by the chemical convulsants pilocarpine and soman, making it useful for studies on neurodegenerative diseases related to the dopamine system.
Smiles
OC=1C=C2[C@H](CN(C)CCC2=CC1Cl)C3=CC=CC=C3
Molecular Formula
C17H18ClNO
Molecular Weight
287.784
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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